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essentials of medical pharmacology

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INTRODUCTION Pharmacology Pharmacology is the science of drugs (Greek: Pharmacon--d.rug; logos-discourse in) . In a broad sense, it deals with interaction of exogenously adrrllnistered chemical molecules (drugs) with living systems. It encompasses all aspects of knowledge about drugs, but most importantly those that are relevant to effective and safe use for medicinal purposes. The two main divisions of pharmacology are pharmacodynamics and pharmacokinetics- Pharmacodynamics (Greek: dynnmis-power) - What the drug does to the body. This includes physiological and biochemical effects of drugs and their mechanism of actionat organ system/ subcellular I macromolecular levels, e.g.- Adrenaline􀂜 interaction with adrenoceptors 􀀦 G-protein mediated stimulation of cell membrane bound adenylyl cyclase􀂜 increased intracellular cyclic 3',5' AMP􀀦 cardiac stimulation,hepatic glycogenolysis and hyperglycaemia,etc. Pharmacokinetics (Greek: Kinesis-movement) - What the body do...

Harsh Mohan - Textbook of Pathology, 6th Edition

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DEFINITION OF PATHOLOGY The word ‘Pathology’ is derived from two Greek words—pathos meaning suffering, and logos meaning study. Pathology is, thus,scientific study of structure and function of the body in disease; or in other words, pathology consists of the abnormalities that occur in normal anatomy (including histology) and physiology owing to disease. Another commonly used term with reference to study of diseases is ‘pathophysiology’ comprised by two words: patho=suffering; physiology=study of normal function. Pathophysiology, thus, includes study of disordered function or breakdown of homeostasis in diseases. Pathologists are the diagnosticians of disease. Therefore, knowledge and understanding of pathology is essential for all would-be doctors,general medical practitioners and specialists since unless they know the causes, mechanisms, nature and type of disease, and understand the language spoken by the pathologist in the form of laboratory reports, they would not be able to ...

K Sembulingam - Essentials of Medical Physiology 6th Edition

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Physiology is the most fascinating and ancient branch of science. It is fascinating because, it unfolds the mystery of complicated functional aspects of individual organs in the body. It is ancient because, it exists ever since the origin of life. Even before knowing the language, culture and society, man knew about the hunger, thirst, pain and fear which are the basics of physiology. Physiology is defined as the study of functions of various systems and different organs of the body. Physiology is of different types namely, Human Physiology, Animal Physiology and Plant Physiology. Human Physiology and Animal Physiology are very much inter-related. Knowledge of Human Physiology is essential to understand the other allied subjects like Biochemistry, Pharmacology, Pathology, Medicine, etc. However, it is worthwhile to have a brief know ledge of anatomy of different systems and various organs to understand the principles of Human Physiology. The basic physiological functions include, pr...

Guyton and Hall Textbook of Medical Physiology 12th Edition

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The goal of physiology is to  explain the physical and chemical factors that are responsible for the origin, development, and progression of life. Each type of life, from the simple virus to the largest tree or the complicated human being, has its own functional characteristics. Therefore, the vast field of physiology can be divided into viral physiology, bacterial physiology, cellular physiology, plant physiology, human physiology, and many more subdivisions. Human Physiology. In human physiology, we attempt to explain the specific characteristics and mechanisms of the human body that make it a living being. The very fact that we remain alive is the result of complex control systems, for hunger makes us seek food and fear makes us seek refuge. Sensations of cold make us look for warmth. Other forces cause us to seek fellowship and to reproduce. Thus, the human being is, in many ways, like an automaton, and the fact that we are sensing, feeling, and knowledgeable beings is part ...

Textbook of Microbiology

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Microbiology is the study of microorganisms, those being unicellular (single cell), multicellular (cell colony), or acellular (lacking cells). Microbiology encompasses numerous sub-disciplines including virology, parasitology, mycology and bacteriology. Eukaryotic microorganisms possess membrane-bound cell organelles and include fungi and protists, whereas prokaryotic organisms—all of which are microorganisms—are conventionally classified as lacking membrane-bound organelles and include eubacteria and archaebacteria. Microbiologists traditionally relied on culture, staining, and microscopy. However, less than 1% of the microorganisms present in common environments can be cultured in isolation using current means. Microbiologists often rely on molecular biology tools such as DNA sequence based identification, example 16s rRNA gene sequence used for bacteria identification. Viruses have been variably classified as organisms, as they have been considered either as very sim...

Gray's Anatomy

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Gray's Anatomy is an English-language textbook of human anatomy originally written by Henry Gray and illustrated by Henry Vandyke Carter. Earlier editions were called Anatomy: Descriptive and Surgical and Gray's Anatomy: Descriptive and Applied , but the book's name is commonly shortened to, and later editions are titled, Gray's Anatomy . The book is widely regarded as an extremely influential work on the subject, and has continued to be revised and republished from its initial publication in 1858 to the present day. The latest edition of the book, the 41st, was published in September 2015 Publication history Henry Gray The English anatomist Henry Gray was born in 1827. He studied the development of the endocrine glands and spleen and in 1853 was appointed Lecturer on Anatomy at St George's Hospital Medical School in London. In 1855, he approached his colleague Henry Vandyke Carter with his idea to produce an inexpensive and accessible anato...