essentials of medical pharmacology
INTRODUCTION Pharmacology Pharmacology is the science of drugs (Greek: Pharmacon--d.rug; logos-discourse in) . In a broad sense, it deals with interaction of exogenously adrrllnistered chemical molecules (drugs) with living systems. It encompasses all aspects of knowledge about drugs, but most importantly those that are relevant to effective and safe use for medicinal purposes. The two main divisions of pharmacology are pharmacodynamics and pharmacokinetics- Pharmacodynamics (Greek: dynnmis-power) - What the drug does to the body. This includes physiological and biochemical effects of drugs and their mechanism of actionat organ system/ subcellular I macromolecular levels, e.g.- Adrenaline interaction with adrenoceptors G-protein mediated stimulation of cell membrane bound adenylyl cyclase increased intracellular cyclic 3',5' AMP cardiac stimulation,hepatic glycogenolysis and hyperglycaemia,etc. Pharmacokinetics (Greek: Kinesis-movement) - What the body do...